“The Strong Pulse”
A potent ghrelin receptor agonist that produces strong GH pulses, though it affects cortisol and prolactin more than Ipamorelin does.
Like Ipamorelin, GHRP-2 activates the ghrelin receptor to trigger GH release, but more forcefully, which is also why it moves cortisol, prolactin, and appetite more than the newer, more selective GHRPs.
Both are ghrelin receptor agonists, but GHRP-2 produces a stronger GH pulse at the cost of more hormonal side effects like elevated cortisol and prolactin.
It's not FDA-approved for human use in the US and is sold as a research chemical. In some other countries it has diagnostic uses under medical supervision.
Short-term studies suggest it reliably raises GH, but the same studies show it affects other hormones too. Long-term human safety hasn't been established.
GHRP-2 has a longer human research history than many GHRPs, including use in some countries as a diagnostic tool for growth hormone deficiency. That gives it more established pharmacology than most peptides here, even though it isn't approved for general use.
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